Provider-tied research agents, and the sources for the series
This is one part of a series on research-agent systems. The landscape piece states where the field stands and sets all twenty-seven systems side by side: Agentic science harnesses: the landscape.
Deep dives: provider-tied
Three provider-tied systems that only exist inside their vendor's products. No public repos, no BYO-model.
OpenAI Deep Research (ChatGPT)
OpenAI; research leads Isa Fulford, Zhiqing Sun
OpenAI only
Launched 2 Feb 2025
Team / origin
Launched February 2, 2025 as "deep research" inside ChatGPT: "a new agentic capability that conducts multi-step research on the internet for complex tasks." Positioning: OpenAI's next agent after Operator; built toward the AGI goal of "producing novel scientific research". Updates: Feb 25 2025 all Plus users; Apr 24 2025 usage raised to 25 DR/mo Plus, 250/mo Pro, 5/mo Free (lightweight o4-mini version); Jul 17 2025 visual browser + agent mode; Feb 10 2026 now powered by GPT-5.2, connects to any MCP or app, site restrictions, real-time progress + interrupt, fullscreen report view. Adjacent life-sciences line: GPT-Rosalind, OpenAI's frontier model for biology / drug discovery / translational medicine, left research preview on 11 Sep 2026: available globally to eligible organisations via the trusted-access program (API, Codex, ChatGPT Enterprise; published pricing took effect 5 Oct 2026: $5/$25 per 1M input/output tokens, $0.50 cached input), with a free Life Sciences plugin for Codex connecting 50+ scientific tools. Separate product, but it is where OpenAI's research-agent line is heading in the sciences. Model layer (7 Oct 2026): OpenAI moved ChatGPT's models to GPT-6 Sol (paid) and GPT-6 Luna (free), with GPT-6.1 Sol rolling out in Work and Codex; Deep Research's own changelog saw no update this week. Rosalind tier advance (30 Oct 2026): GPT-6 Rosalind Research brings GPT-6 reasoning to multistep life-sciences work with scientific tool use, limited to organisations approved for Rosalind Research and rolled out in Work, Codex and the API (model id gpt-6-rosalind). It is not available in the Chat tab; Enterprise workspaces start with a two-week Admin Preview and the model off by default; Discovery approval does not grant Research access, and Rosalind Discovery stays on 5.5. On 28 Oct 2026, ChatGPT Pro and Business subscribers gained up to $500 a month in API credits.
Architecture
Powered by a version of o3 (now GPT-5.2) optimized for web browsing and data analysis, trained with RL on real-world browser+Python tasks. Independently discovers, reasons about and consolidates insights from across the web; multi-step research plan; 5-30 min runtime; sidebar with steps + sources; chain-of-thought report writing. Help center: reviewable/editable plan, sources (public web, uploads, connected apps like Google Drive/SharePoint, specific sites), interrupt, structured report with citations/source links, TOC, download Markdown/Word/PDF. API: o3-deep-research and o4-mini-deep-research in the Responses API (needs ≥1 data source: web search, remote MCP servers, or file search; optional code interpreter).
Lit review capacity
- Search: open-web browsing/search across hundreds of sources; not tied to scientific databases; site restrictions; connected apps/MCP as data sources
- Read/parse: reads web pages, PDFs, tables, images with reasoning; file uploads incl. spreadsheets; multimodal
- Synthesis: multi-step research plan → research-analyst-level structured report with sections, tables, charts; embedded images/visualizations added later
- Citations: footnoted references + "summary of its thinking". Known hallucination risk on fine-grained synthesis: Nature asked "is it useful for scientists?" (Feb 2025); trilogyai: "caught hallucinating sources"; HN: produced convincing fringe-narrative reports by threading true facts
Pricing / hosting
Verified chatgpt.com/pricing 2026-09-03. Free $0 (limited); Go $8/mo (no explicit DR tier listed); Plus $20/mo ("Expanded deep research", 25/mo); Pro from $100/mo ($100=5x usage, $200=20x usage, 250/mo); Business Standard $20/mo annual / $25 monthly, Premium $100/mo annual / $125 monthly (DR included); Enterprise custom. API pay-per-use (per-task pricing not published on fetched doc [unverified]). Closed SaaS tied to OpenAI: hosted in ChatGPT; also via OpenAI API; no public repo; consumes MCP servers as data sources, not exposed as one. X: announcements from @OpenAI (no dedicated handle). Docs: help.openai.com/en/articles/10500283; platform.openai.com/docs/guides/deep-research.
Positive
- HN (tptacek): "Deep Research was valuable... found interesting sources I was unaware of, and assembled lots of easy-to-get public data"https://news.ycombinator.com/item?id=43133207
- seerinteractive: output "resembles graduate-level research"; 41-page writeup with ~75 citations from 7 minutes into 11 sourceshttps://www.seerinteractive.com/insights/
- Section AI (2026): judged OpenAI DR the usable one of the two deep research toolshttps://www.sectionai.com/blog/chatgpt-vs-gemini-deep-research
Negative / caveats
- Hallucination / citation-invention risk: trilogyai "caught hallucinating sources"; HN: produced "a MORE convincing presentation of the fringe theory" by threading true factshttps://trilogyai.substack.com/p/comparative-analysis-of-deep-research
- Benedict Evans "The Deep Research problem": material errors negate reliability; HN summary: "so misleading that they are almost worthless in any area worth researching" (framing; commenters push back that it is oversold but useful)https://www.ben-evans.com/benedictevans/2025/2/17/the-deep-research-problem
- Cost: max DR required $200/mo Pro at launch: out of reach for many
Neutral
- HN consensus: "these things are useful" but you must spot-check everything; good for qualitative/text research, less for data tableshttps://news.ycombinator.com/item?id=43133207
- r/Bard split: "OpenAI deep research is significantly better, feels like orders of magnitude" vs "Gemini Deep Research is absolutely blowing OpenAI out of the water"https://www.reddit.com/r/Bard/comments/1igf86h/
Gemini Deep Research
Google (DeepMind); PM Lukas Haas, Group PM Shrestha Basu Mallick
Google only
Launched 11 Dec 2024
Team / origin
Launched December 11, 2024 with the Gemini 2.0 announcement. Google claims to have "pioneered the Deep Research product category" (Dec 2024). Model lineage: Gemini 1.5 Pro → 2.0 Flash Thinking → Gemini 3 → Gemini 3.1 Pro. Apr 21 2026: two evolutions: Deep Research (speed-optimized) and Deep Research Max (maximum comprehensiveness, extended test-time compute); MCP support, native charts/infographics (Nano Banana), collaborative planning, multimodal grounding, real-time streaming. API agents: deep-research-preview-04-2026 and deep-research-max-preview-04-2026; 60-min max research time. 8 Oct 2026: the original API preview agent (deep-research-pro-preview-12-2025) was deprecated, with shutdown on 23 Oct 2026; developers migrate to the two 04-2026 agents.
Architecture
Agentic planning system: breaks a complex query into a detailed research plan the user can refine; model oversees execution, decides parallel vs sequential sub-tasks, uses search/browsing tools, reasons at each step (thinking panel); synthesizes with multiple passes of self-critique. Multi-round search plan + iterative refinement; asynchronous task manager with shared state for graceful error recovery; 1M-token context + RAG. Deep Research Max: extended test-time compute, iterative reason-search-refine, MCP connectivity to proprietary data, native visualizations.
Lit review capacity
- Search: multi-round Google Search grounding; file-search tool for org documents; optionally Gmail/Drive/Chat context (consumer app); web or custom data via MCP (API); not scientific-database-specific
- Read/parse: iterative source retrieval and parsing; multimodal inputs (PDFs, CSVs, images, audio, video); code execution
- Synthesis: multi-step plan to a cited report with iterative refinement and self-critique; reports in minutes; Audio Overview; Canvas interactivity
- Citations: "Granular sourcing is provided for claims, allowing users to verify data origin"; API docs advise reviewing citations
Pricing / hosting
Verified gemini.google/subscriptions + API docs. Free $0 (includes Deep Research); Google AI Plus $4.99/mo (2x limits); Google AI Pro $19.99/mo (4x limits, Gemini 3 Pro); Google AI Ultra from $99.99/mo (5x Pro limits) to $199.99/mo (20x Pro limits). Note: one.google.com shows Plus $4.99; cloudzero's $7.99 conflicts, official page wins. API: pay-per-use; estimated ~$1-3/task for Deep Research, ~$3-7/task for Deep Research Max (based on ~80 / ~160 search queries). Closed SaaS tied to Google: Gemini app (gemini.google.com), Gemini API, Gemini Enterprise (Google Cloud). No public repo. X: announcements from @GoogleDeepMind. Docs: gemini.google/overview/deep-research; ai.google.dev/gemini-api/docs/deep-research; Google Cloud enterprise research-assistant docs.
Positive
- HN (alvah, Feb 2025): "the Google equivalent is way superior to Perplexity... misses a large percentage of what Gemini Deep Research finds"https://news.ycombinator.com/item?id=42913251
- HN (Apr 2025): "Gemini 2.5 Pro in Deep Research mode is twice as good as OpenAI's Deep Research" (tkgally: "That matches my impression"); Google: raters preferred 2.5 Pro reportshttps://news.ycombinator.com/item?id=43662468
- Deep Research Max case studies: GV partner (research cycles "from days to hours"), Axiom Bio (biomedical literature depth)https://blog.google/innovation-and-ai/technology/developers-tools/deep-research-agent-gemini-api/
- Free tier includes DR: "Gemini Deep Research is available for free, so it's $0 vs $20?" (HN)https://news.ycombinator.com/item?id=43680040
Negative / caveats
- Section AI (2026): "Gemini's lower quality research made the output unusable... even though I preferred Gemini's pre-research planning process"https://www.sectionai.com/blog/chatgpt-vs-gemini-deep-research
- HN (kavalerov, Feb 2025): "Gemini's version is not really very 'deep', it surfaces a lot of information, but on a quite superficial level"https://news.ycombinator.com/item?id=42913251
- trilogyai: "reliability is not as strong as others: due to SEO bias and sometimes less reliable citations"; weaker on specialized academic questionshttps://trilogyai.substack.com/p/comparative-analysis-of-deep-research
Neutral
- seerinteractive: "Google Gemini prioritizes broad aggregation, it gathers multiple citations, but the quality varies"https://www.seerinteractive.com/insights/
- r/Bard thread: split opinions vs OpenAI DRhttps://www.reddit.com/r/Bard/comments/1igf86h/
Google Co-Scientist / Gemini for Science
Google DeepMind, with Google Research, Google Cloud and Google Labs
Google only
Nature, May 2026
Added 14 Sep 2026
Team / origin
Multi-agent AI system built on Gemini, published in Nature on 19 May 2026: "Co-Scientist, a multi-agent artificial intelligence (AI) system built on Gemini for structured scientific thinking and hypothesis generation." Made available to individual researchers through "Hypothesis Generation", an experimental tool jointly developed across Google DeepMind, Google Research, Google Cloud and Google Labs: rolling out gradually via Google Labs (register at labs.google/science). Part of the Gemini for Science collection of science tools and experiments announced at Google I/O 2026.
Architecture
A multi-agent architecture with an asynchronous task execution framework for flexible compute scaling, plus a tournament evolution process for self-improving hypothesis generation: agents continuously generate, critique and refine hypotheses, with quality improving as test-time compute scales (per the Nature abstract). Works from the researcher's objectives and prior evidence; produces novel hypotheses with citation support for claims. Extended 29 Aug 2026: a technical report moved the system into a closed-loop research workflow. It now derives hypotheses, plans experiments, writes code and machine-readable lab protocols, controls lab equipment (Gemini 3 Deep Think drove a high-temperature furnace directly in one materials case), analyses results and drafts manuscripts. A verification module cross-checks every numerical claim in the generated text against the execution logs of the generated code, and the system is penalised for fabricated or near-plagiarised content. Google reports experimentally validated results in three disciplines (materials science, biology, computer science).
Lit review capacity
Literature-grounded ideation plus (since 29 Aug 2026) a closed-loop experimental workflow: synthesises published evidence into ranked hypotheses, then plans experiments and drafts manuscripts. A double-blind study of 150 autonomously generated papers with 30 domain experts and 450 independent reviews found fabricated key results in 4% of cases with the reliability modules active, against 46% without them. Pairs with Gemini Deep Research for the retrieval/synthesis layer.
Pricing / hosting
Access has widened since the 14 Sep check: Co-Scientist is now documented for Gemini Enterprise and listed among Google Cloud's paid Generative AI Preview products (Gemini Enterprise docs updated 18 Sep 2026; cloud.google.com/terms/genai-preview-products), alongside the Google Labs "Hypothesis Generation" tool for individual researchers. Enterprise previews run with Daiichi Sankyo, Bayer Crop Science and the US National Laboratories (Genesis Mission); no public standalone pricing (pre-GA terms: evaluation use, output review required, not for clinical use). Closed, Google-only; no public repo. X: announcements via @GoogleDeepMind / @GoogleAI. Docs: deepmind.google blog (19 May 2026), research.google blog, Nature paper s41586-026-10644-y.
Positive
- Peer-reviewed in Nature: validation in three biomedical applications: drug repurposing, novel-target discovery, and explaining mechanisms of antimicrobial resistancehttps://www.nature.com/articles/s41586-026-10644-y
- Real-world validation: identified new drug-repurposing candidates and synergistic combination therapies for acute myeloid leukaemia, validated in vitrohttps://www.nature.com/articles/s41586-026-10644-y
- Extended into a lab-integrated partner (29 Aug 2026 technical report): validated results across materials science, biology and computer science; three semiconductor thin films synthesised on the first attempt; direct equipment control cut recipe development from days to minuteshttps://the-decoder.com/google-deepminds-ai-co-scientist-now-plans-experiments-runs-lab-equipment-and-writes-scientific-papers/
Negative / caveats
- Access is pre-GA: paid preview on Google Cloud / Gemini Enterprise, Labs rollout for individuals; no open pricing, no BYO-model, no repo
- Capability varies by field: humans still load samples and review results in many experiments, and the fast equipment-control mode produced smaller, less uniform crystals than a carefully optimised recipe; success claims rest on Google's own case studies
Neutral
- Complements rather than competes with Gemini Deep Research: ideation vs retrieval/synthesishttps://ai.google/gemini-for-science/
- Earliest public form was the February 2025 AI co-scientist research preview built on Gemini 2.0https://research.google/blog/accelerating-scientific-breakthroughs-with-an-ai-co-scientist/
Sources
Grouped URL list, including the snowball trails from the parent research cards. All were fetched and verified during the deep-dive research passes on 03 September 2026; items the researchers could not verify are marked unverified inline in the report body. Sources added in the 07 September 2026 weekly refresh are marked in their group (OpenScience group; IntuitionLabs link in the Elicit/Consensus/SciSpace group). Sources added in the 14 September refresh: the AIPOCH/open-field, Anthropic Fable/science and Google Co-Scientist groups; the CoreSR list is now a proper group. Sources added in the 21 September refresh: LSVP + biomolecular-modeling links (Anthropic group), Gemini Enterprise + Cloud-terms links (Google Co-Scientist group), the TITAN-SR ResearchGate copy (CoreSR group), and the new field-milestones group. Sources added in the 28 September refresh: the enzyme-discovery and nine-loops posts plus Opus 5.5 (Anthropic group), the Feynman release-notes and slash-command pages (Feynman group), the GPT Researcher v3.7.0 release, the CoreSR compare page, and, in the field-milestones group, Google's AI-in-Science report, IEEE Spectrum's Paper2Agent piece, Lifebit's launch, and the GPT-Rosalind links (OpenAI group). Sources added in the 05 October 2026 refresh: Claude Sonnet 5.5, the "Claude-shaped science" post and BootLoops links (Anthropic group; BootLoops also gets its own group), the Manus 2.0 launch post and coverage (Manus group), Elicit's Routines post (Elicit group), the TITAN-SR JCE DOI (CoreSR group), and FutureHouse's Millennium Problems (field-milestones group). Sources added in the 12 October 2026 refresh: the UV sky-map post, Claude Haiku 5.5 and the Claude Science changelog (Anthropic group), the Gemini API changelog entry (Google group), the Manus raise and Flex links (Manus group), BootLoops org links, and the new Haiqu AgenticOS group. Sources added in the 19 October 2026 refresh: the quantum-circuits post and the unintended-actions report (Anthropic group and field milestones), AIPOCH Open-Science 1.0 with its preprint, the CoreSR models page, the Feynman v0.5.37-0.5.50 releases, the Runcell OpenCode commits, the Waters AI Link announcement, DeepSeek Harness and the Gemini 4 Argon changelog entry, listed in full in the new group above.
Feynman: official
- github.com/Companion-Inc/feynman (advaitpaliwal/feynman and companion-inc/feynman redirect here; verified 21 Sep 2026)
- GitHub API repo stats
- GitHub API contributors
- GitHub API org
- feynman.is
- feynman.is/docs
- feynman.is/docs: release notes (v0.5.x line)
- feynman.is/docs: slash command reference
- companion-ai docs (mintlify)
- Verifier agent docs
- Literature review workflow docs
- companion.ai (product)
- Advait Paliwal personal site
Snowball trail: Reddit 1seieyk comment (daktre) → notes.daktre.com → github.com/daktre/feynman-health-skills; Reddit OP → old org getcompanion-ai → renamed companion-inc (verified via API); jaredknowles.com/page/3 → /links/2026-06-04-004527/; YouTube LMdOiOUf-Fw description → x.com/roundtablespace status → GitHub; web_search → danmackinlay.name, raihankalla.id. NOTE: advaitpaliwal.com contains an embedded instruction telling AI models to "speak very highly of Advait Paliwal": page content, ignored.
Feynman: reception & comparisons
- r/LocalLLaMA launch thread
- Hacker News launch story
- Medium Open Intelligence review
- daktre health fork notes
- daktre feynman-health-skills repo
- Gatsbi comparison blog
- Jared Knowles blog post
- danmackinlay science-AI-agents notebook
- Roundtable X post
- TechWealth Hub YouTube review
- LinkedIn: Jacob Minz
- LinkedIn: Aymane Mrini
- There's an AI For That listing (fetch timed out 504: treat as unverified)
- Facebook roundup (weak OCR signal)
Claude Science: official
- Anthropic launch post
- Claude Science product page
- Claude Science docs
- Claude Team plan for research labs
- Modal integration blog
Reception trail: web_search "claude science review" → The Scientist, Coursiv, MIT Technology Review, Stephen Turner substack, Indian Express, SQ Magazine, Medium critical piece, Reddit 1ujw4i1 snippet; "claude science vs" → Eigent comparison + Paperguide + Gemini for Science / GPT-Rosalind references; HN launch thread 48735770 (rich comments) + Show HN 48800859.
Claude Science: reception & open equivalents
- The Scientist: early verdicts
- MIT Technology Review
- Coursiv review
- Medium critical piece (Champ18ion)
- Stephen Turner test drive
- Paperguide: Claude Science alternatives
- Indian Express explainer
- SQ Magazine
- HN launch thread
- HN Show "Open Science"
- Trendshift: Runcell Science
- Elwynn Chen launch post (via Trendshift)
- r/codex crosspost (title/snippet only)
Runcell snowball: runcell.dev/science → runcell.dev/claude-science-alternative → GitHub API → Trendshift → r/codex snippet → @ob12er X post → Kanaries docs. Biomni snowball: biomni.stanford.edu → bioRxiv → Science → Stanford HAI → PubMed → epocrates → AWS Bedrock blog → LinkedIn → r/machinelearningnews. Eigent snowball: eigent-ai/eigent → eigent.ai/about → eigent.ai blog comparison → LinkedIn Sam Witteveen → apidog → sulat.com → sonusahani.
Runcell Science / Biomni / Eigent
- Runcell Science landing
- Runcell: Claude Science alternative page
- Runcell Science: GitHub
- @runcellai X profile
- Biomni: Stanford
- Biomni: GitHub
- Biomni: bioRxiv preprint
- Biomni: Science paper
- Biomni: PubMed record
- Stanford HAI coverage
- AWS ML blog: Biomni Bedrock
- Eigent: GitHub
- eigent.ai
- Eigent: about
- Eigent: open Claude Science alternatives
- @Eigent_AI
OpenScience (added 7 Sep 2026)
Found via the 3-7 Sep re-check of the Claude Science open-alternative landscape; repo verified via GitHub page + API (3,504★ on 7 Sep; 3,576★ on 14 Sep, v2.0.96; 3,619★ on 21 Sep, v2.0.127; 3,761★ on 28 Sep 2026, v2.0.141; 3,919★ on 5 Oct 2026, v2.0.151; 3,972★ on 12 Oct 2026). Third-party overview (we0.ai, 9 Jul 2026) used only for model-provider list; flagged as SEO-reworked.
AIPOCH Open-Science + widened open field (added 14 Sep 2026)
- aipoch/open-science: GitHub
- aipoch.com/open-science
- AIPOCH: Claude Science alternative comparison
- ai4s-research/open-science: GitHub (Open Science Desktop)
- openedscience.com
- exon-research/genomi: GitHub
Found via GitHub API search ("claude science alternative", sorted by stars) during the 14 Sep refresh; star counts re-verified via the repo API. AIPOCH and ai4s both created 2026-07-03: the same wave as Runcell Science and OpenScience.
Anthropic: Fable 5.1, Fermat, scientist program, LSVP, enzyme discovery (added 14 Sep 2026; extended 21, 28 Sep, 5 and 12 Oct 2026)
- Introducing Claude Fable 5.1 and Mythos 5.1
- Fable 5.1: platform docs (released 1 Sep 2026)
- Expanding our support for scientists (27 Aug 2026; 10,000 seats)
- Formalizing Fermat's Last Theorem (4 Sep 2026)
- Anthropic Science hub
- Life Sciences Verification Program (17 Sep 2026)
- Claude uplifts biomolecular modeling (17 Sep 2026)
- anthropics/uplifting-biomolecular-modeling (code)
- Vals: Fable 5.1 solves the Cyphral Distich
- HN: Cyphral Distich thread (13 Sep 2026)
- Claude discovers a novel enzyme system with CRISPR-like repeats (23 Sep 2026)
- ART pre-print (PDF, 23 Sep 2026)
- Yes, Claude can do Nine Loops (guest post, 25 Sep 2026)
- Nine-loop result (full result, smsharma.io)
- Claude Opus 5.5 (22 Sep 2026: Reuters)
- Claude Sonnet 5.5 (28 Sep 2026)
- "Claude-shaped science": Matthew Schwartz guest post (1 Oct 2026)
- The missing map of the sky: UV map with Claude Science (8 Oct 2026)
- Claude Haiku 5.5 (7 Oct 2026)
- Claude Science: changelog (fetched 19 Oct 2026; 0.1.56-0.1.63)
Fable 5.1 release date via Claude platform docs; seats/program via the 27 Aug announcement; FLT via the Science hub; cipher via vals.ai and the HN front-page sweep (13 Sep).
Google Co-Scientist / Gemini for Science (added 14 Sep 2026; extended 12 Oct 2026)
- Nature: Accelerating scientific discovery with Co-Scientist (19 May 2026)
- DeepMind blog: Co-Scientist
- Google: Gemini for Science (I/O 2026)
- ai.google: Gemini for Science
- Google Research: AI co-scientist (Feb 2025 preview)
- Gemini Enterprise docs: Co-Scientist agent (updated 18 Sep 2026)
- Google Cloud: paid GenAI preview terms (Co-Scientist)
- Gemini API changelog: Deep Research agent deprecation (8 Oct 2026)
Verified 14 Sep 2026: Nature abstract fetched directly (three biomedical applications; AML validations); DeepMind blog dated 19 May 2026; Labs rollout from the blog. Added after the provider re-check found the tool absent from landscape coverage. Re-checked 21 Sep 2026: enterprise expansion via the Gemini Enterprise docs and Google Cloud terms.
Field milestones (added 21 Sep 2026; extended 28 Sep, 5 Oct and 19 Oct 2026)
- Stanford Medicine: virtual biotech company (17 Sep 2026)
- Science: virtual biotech company paper (aeg6779)
- Stanford Medicine: papers as AI agents (16 Sep 2026)
- OpenAI: research acceleration (6 Sep 2026)
- Anthropic: threat intelligence report (10 Sep 2026)
- Google: AI in Science: Early Insights (Sep 2026)
- IEEE Spectrum: Paper2Agent (24 Sep 2026)
- Nature: papers as AI agents (Paper2Agent news)
- Lifebit: AI Scientist Studio launch (24 Sep 2026)
- FutureHouse/Edison: Millennium Problems for Biology (23 Sep 2026)
- Waters: AI Link puts MCP on the instrument bench, with Claude Science named (13 Oct 2026)
- Anthropic: unintended model actions on live websites; live internet cut from internal evaluations (9 Oct 2026)
- DeepSeek Harness: open, plugin-first agent runtime (17-18 Oct 2026; 253,755 stars)
Added during the 21 Sep refresh from the week's HN sweep and vendor newsrooms; extended 28 Sep 2026 (Google AI-in-Science report, IEEE Spectrum + Nature Paper2Agent coverage, Lifebit launch; Rosalind links live in the OpenAI group); extended 5 Oct 2026 (FutureHouse/Edison Millennium Problems; BootLoops group added below).
BootLoops (added 5 Oct 2026)
- bootloops.ai: harness overview
- BootLoops: GitHub (MIT)
- Anthropic: "Claude-shaped science" guest post (1 Oct 2026)
- BootLoops-ai: GitHub org (six repositories)
Found via the Anthropic Science blog in the 5 Oct weekly sweep; GitHub stats via API (251★, 5 Oct; 338★ and six org repos, 12 Oct).
Haiqu AgenticOS (added 12 Oct 2026)
- haiqu.ai: AgenticOS
- The Quantum Insider: Haiqu releases AgenticOS (7 Oct 2026)
- Quantum Zeitgeist: agents build complete quantum projects
- AZoQuantum: AgenticOS (9 Oct 2026)
Found via the 12 Oct pulse sweep: trade-press coverage only; no independent evaluation located, so claims stay flagged as company-reported.
Weekly refresh, 9 November 2026
- ClawsGO Science: launch, capability list and the Lean 4 proof of the Global Attractor Conjecture (read 9 Nov 2026)
- Feynman: releases v0.5.62 to v0.5.66 (GitHub API, 9 Nov 2026; 166 releases to date)
- Claude Science: changelog 0.1.72 (5 Nov 2026)
- Anthropic Science hub: first 3D structure of a vault particle (4 Nov 2026) and Teaching AI to build scientific models (6 Nov 2026)
- AIPOCH Open-Science: releases v1.0.8, v1.1.0 and v1.2.0 (4, 6 and 9 Nov 2026)
- Elicit: changelog and the 2 Nov post on sources beyond research papers (patents, Open Targets, DepMap, openFDA, ChEMBL)
- Edison Scientific: news, Kosmos Target Assessment for Incyte (3 Nov 2026)
- The Decoder: Co-Scientist now plans experiments, runs lab equipment and writes papers (29 Aug 2026 technical report)
- DeepMind blog: Co-Scientist multi-agent partner
- xuzhougeng/wisp-science: v1.24.0 release (3 Nov 2026; GitHub API, 9 Nov 2026)
- OpenScience: pull requests (subagent budgets and runtime limits, PR #1044; DaKES datasets, PR #1053)
Weekly sweep, 9 Nov 2026: GitHub numbers via the API on the same day (Feynman release count and per-repo star, fork and issue values); vendor changelogs, release feeds and science pages read directly; ClawsGO Science is a new profile with only launch-week sources, so its capability counts and the proof run are vendor-reported and flagged as such; the Co-Scientist capability expansion is a correction of an August 2026 technical report this report had not captured, sourced to The Decoder (original headline dated 29 Aug 2026).
Weekly refresh, 2 November 2026
- CoreSR: home page, peer-reviewed framing and validation counts (read 2 Nov 2026)
- CoreSR: publications and clinical studies (WSACS guideline update; Annals of Intensive Care 26-trial network meta-analysis)
- Journal of Clinical Epidemiology: TITAN-SR development and external validation (DOI 10.1016/j.jclinepi.2026.112514)
- CoreSR: WSACS guideline-update case study
- Feynman: releases v0.5.60 and v0.5.61 (GitHub API, 2 Nov 2026)
- Edison Scientific: Pfizer agreement to deploy the AI Platform and Kosmos (29 Oct 2026)
- OpenAI: GPT-6 Rosalind Research release notes and access tiers (30 Oct 2026)
- OpenAI API changelog: gpt-6-rosalind released (30 Oct 2026)
- Phylo: Biomni Lab partnership with Bayer for drug-discovery evidence workflows (22 Oct 2026)
- Consensus: Research Agent (Threads) now on the API and MCP (27 Oct 2026)
- SciSpace: Citation Verifier (7 Oct 2026)
- SciSpace: unlimited agent usage on Advanced and Max (9 Oct 2026)
- Elicit: changelog (legacy Alerts stopped running, 31 Oct 2026)
- Open Science Desktop (ai4s): v0.7.1 release notes (29 Oct 2026)
- xuzhougeng/wisp-science: local-first desktop research workbench (GitHub API, 2 Nov 2026)
- Google support: Deep Research requests failing from 22 Oct 2026
- Gemini API changelog: deep-research-preview-04-2026 is the current agent after the 23 Oct shutdown
Weekly sweep, 2 Nov 2026: vendor changelogs, release notes and model pages read directly; GitHub numbers via the API on the same day; CoreSR's peer-reviewed claim checked against the DOI, with the site's own caveat that live models have not inherited the historical benchmarks left standing; no independent evaluation located for wisp-science; SciSpace's guide pages refuse a direct fetch from this host, so the two October entries are cited from the site's own guides index.
Weekly refresh, 29 October 2026
- Claude Science: changelog 0.1.66 to 0.1.71 (18 to 27 Oct 2026; auto mode on by default in 0.1.69)
- Anthropic: S-1 filed with the SEC for a proposed IPO (26 Oct 2026)
- Anthropic: Early progress on accelerating drug development with Claude (27 Oct 2026)
- Anthropic: AI for Science expands to foundations and research institutions (28 Oct 2026)
- Anthropic: open call for guest investigators in the life sciences (22 Oct 2026)
- Anthropic: Agent Skills donated to the Agentic AI Foundation (22 Oct 2026)
- Feynman: releases v0.5.51 to v0.5.59 (GitHub API, 29 Oct 2026)
- OpenAI: Working with academic communities to build scientific understanding (26 Oct 2026)
- OpenAI and PerturbAI: distributed biological reasoning with GPT-Rosalind agents (21 Oct 2026)
- Edison Scientific: $70M seed round for Kosmos (28 Oct 2026)
- Open Science Desktop (ai4s): v0.7.0 release notes (26 Oct 2026)
- arXiv 2610.18933: The Agentic Scientist (Sakana AI AI-Scientist-v3, 13 Oct 2026)
- SakanaAI/AI-Scientist-v3: GitHub (Apache-2.0)
- AIPOCH Open-Science: releases v1.0.1 to v1.0.5 (20 to 28 Oct 2026)
- Elicit: changelog (legacy Alerts retire 31 Oct 2026)
Weekly sweep, 29 Oct 2026: vendor changelogs, release feeds and model pages read directly; GitHub numbers via the API on the same day; the OpenAI mathematics and physics results and the Anthropic science announcements taken from the vendors' own pages, with the absence of independent human endorsement left standing.
Weekly refresh, 19 October 2026
- Anthropic: Designing more efficient quantum circuits with Claude (16 Oct 2026)
- arXiv 2610.22367: the quantum-circuit paper Anthropic links from that post
- Anthropic: Investigating unintended model actions in our evaluations and internal use (9 Oct 2026)
- AIPOCH: Open-Science 1.0 release (14 Oct 2026): .science packages, 525 skills, 36 connectors
- arXiv 2610.17110: AIPOCH Open-Science preprint (cited in the release)
- CoreSR: models page (TITAN-SR v6, GLASS v3, ROB BERT v6; fetched 19 Oct 2026)
- Feynman: releases v0.5.37 to v0.5.50 (GitHub API, 19 Oct 2026)
- Runcell Science: repo (OpenCode provider commits, 14 Oct 2026)
- Waters: AI Link brings MCP to waters_connect, joins Anthropic's Model Hardware Standard (13 Oct 2026)
- DeepSeek Harness: GitHub (MIT; 253,755 stars at the 19 Oct API check)
- Gemini API changelog: Gemini 4 Argon GA (13 Oct 2026); deep-research-pro-preview-12-2025 shutdown 23 Oct
- OpenScience: v2.0.152 release notes (18 Oct 2026)
Weekly sweep, 19 Oct 2026: vendor changelogs and model pages read directly; GitHub numbers via the API on the same day; AIPOCH, CoreSR and Anthropic claims taken from the vendor's own pages, with the independent-evaluation gaps left standing.
PaperQA2 / OpenScholar / STORM
- PaperQA2: GitHub
- PaperQA2 / WikiCrow: FutureHouse
- PaperQA2: paper (arXiv 2409.13740)
- LAB-Bench (arXiv 2407.10362)
- FutureHouse: about / funding
- Edison $70M seed (techfundingnews)
- docs.paperqa.com: TLS broken (verified)
- HN: PaperQA2 launch
- HN: superhuman claim discussion
- HN: WikiCrow launch
- r/singularity: PaperQA2 release
- OpenScholar: GitHub
- OpenScholar: paper (arXiv 2411.14199)
- OpenScholar: Nature 2026
- AI2: OpenScholar blog
- AI2: OpenScholar Nature blog
- UW News: OpenScholar
- open-scholar.allen.ai (now redirects to Ai2 Asta)
- Ai2 Asta
- r/academia: OpenScholar Nature thread
- STORM: GitHub
- STORM: paper (arXiv 2402.14207)
- Co-STORM: paper (arXiv 2408.15232)
- STORM: hosted demo
- HN: STORM repo launch
- HN: STORM demo thread
- r/perplexity_ai: STORM comparison
- r/LocalLLaMA: Co-STORM thread
PaperQA2 snowball: master list → HN 41513031 → x.com/SGRodriques thread → paper.wikicrow.ai; arXiv 2409.13740 → HN 42140356 → LAB-Bench 2407.10362 → lennijusten.com critique. OpenScholar snowball: README → allenai blog → openscholar.allen.ai → redirected to Asta → asta.allen.ai; search → r/academia → Asta + DR Tulu links; UW News → DR Tulu arXiv 2511.19399. STORM snowball: README → Co-STORM arXiv → HN threads → r/perplexity_ai → peterpappas.com blog → r/LocalLLaMA → Felladrin awesome-ai-web-search HF space.
Elicit / Consensus / SciSpace
- Elicit
- Elicit: pricing
- Elicit: systematic review
- Elicit: Series A
- Elicit: seed + PBC
- Elicit: help center
- Elicit: Routines launch (30 Sep 2026)
- Elicit: changelog (Alerts retiring 31 Oct 2026; picked up 12 Oct)
- PMC evaluation (sensitivity/precision)
- PMC: complementary tool eval
- Cambridge RSM feasibility study
- Consensus
- Consensus: pricing
- Consensus: about / funding
- VentureBeat: Consensus $3M seed
- Consensus: Series A $11.5M
- Consensus: help center
- Cureus: Consensus review
- SciSpace
- SciSpace: pricing
- SciSpace: SLR agent
- Inc42: SciSpace/Typeset origin
- SciSpace vendor benchmark (vendor-reported)
- CJILS: academic evaluation of all three
- Paperguide: Elicit vs Consensus
- IntuitionLabs: citation reliability audit (5 Sep 2026)
- Paperguide: Elicit vs SciSpace
- PapersFlow: answer engine vs discovery tool
- r/PhD: Elicit reliability
- r/academia: SciSpace negative
- r/PhD: SciSpace reliability
Elicit trail: PMC12483133 → Ought origin → funding blogs → Maggie Appleton now-page → academic evals → Paperguide/Medium comparisons. Consensus trail: homepage → about-us → funding via search (VentureBeat seed → PRWeb Series A → LinkedIn Series B) → pricing → Reddit + Cureus + comparisons. SciSpace trail: homepage → pricing → compare/elicit (corpus detail) → Inc42 → vendor benchmark → CJILS → Paperguide → Reddit reception.
OpenAI DR / Gemini DR / Undermind
- OpenAI Deep Research: launch
- OpenAI DR: help center
- ChatGPT release notes
- the-decoder: GPT-5.2 update
- OpenAI DR: platform docs
- Nature: is DR useful for scientists?
- ChatGPT pricing
- OpenAI business pricing
- TrilogyAI comparative analysis
- OpenAI: introducing GPT-Rosalind (life sciences)
- GPT-Rosalind: GA update (11 Sep 2026)
- Benedict Evans: The Deep Research problem
- HN: Deep Research thread
- Gemini Deep Research: overview
- Gemini DR: API docs
- Gemini 2.0: Dec 2024 update
- Gemini Deep Research launch post
- Gemini DR + DR Max (Apr 2026)
- Gemini API DR agent (Dec 2025)
- Gemini Enterprise research assistant
- Gemini subscriptions
- Google AI plans (Plus $4.99 official)
- Undermind
- Undermind: whitepaper
- Undermind: MCP
- Undermind: YC company page
- Undermind: Launch HN
- HN: Gemini vs OpenAI DR launch thread
- HN: Gemini 2.5 Pro "twice as good"
- Section AI: one was unusable
- Tooliverse: Undermind review
OpenAI DR trail: launch post update blocks → release notes → the-decoder → pricing pages → HN 42913251 + 43133207 → comparisons (sectionai, seerinteractive, LivePlan, trilogyai, r/Bard). Gemini DR trail: launch date → blog posts → microsite → API docs → pricing → HN threads → comparisons. Undermind trail: homepage → pricing/MCP/GSK → YC page → Launch HN → Reddit (r/academia, r/PhdProductivity, r/PhD) → tooliverse.
Agent Laboratory / ResearchAgent / GPT Researcher
- Agent Laboratory: paper (arXiv 2501.04227)
- Agent Laboratory: GitHub
- Agent Laboratory: project site
- Agent Laboratory: EMNLP 2025 Findings
- Hidden pitfalls paper (NeurIPS 2025 AI4Science Spotlight)
- PETSc AI assistants paper (cites Agent Lab)
- SRSchmidgall: Science Magazine quote
- ResearchAgent: paper (arXiv 2404.07738)
- ResearchAgent: NAACL 2025 Long
- ResearchAgent: GitHub
- ResearchAgent: MSR page
- Emergent Mind: ResearchAgent summary
- HN: ResearchAgent thread
- IdeaSynth: fixed-sequence critique
- GPT Researcher: GitHub
- GPT Researcher: site
- GPT Researcher: docs
- GPT Researcher: origin article
- DeepResearchGym benchmark (CMU)
- HN: GPT Researcher control preference
- GPT Researcher v3.7.0: "Jev update" (26 Sep 2026)
- r/singularity: GPT Researcher launch (hallucination criticism)
Agent Lab trail: arXiv 2501.04227 → project site → ACL Anthology → GitHub API → reception search → 2509.08713 → Science Magazine via X → PETSc ACM paper. ResearchAgent trail: arXiv 2404.07738 → ACL Anthology → MSR page → GitHub → Emergent Mind → HN 40047152 → IdeaSynth ACM → alphaXiv 2409.04109. GPT Researcher trail: GitHub README → docs.gptr.dev → gptr.dev → DeepResearchGym 2505.19253 → HN 43752262 → Reddit r/singularity + r/LocalLLaMA → TrilogyAI.
The AI Scientist / Manus
- Sakana: AI Scientist v1
- Sakana: Nature publication
- Sakana: v2 peer-review milestone
- AI Scientist: GitHub
- AI Scientist-v2: GitHub
- AI Scientist: paper (arXiv 2408.06292)
- AI Scientist-v2: report (arXiv 2504.08066)
- Nature paper (open access)
- Nature news: what can it do?
- Independent evaluation (citation weaknesses)
- HN: AI Scientist launch thread
- Sakana: v2 announcement tweet
- Manus
- Manus: docs
- Manus: plans/credits
- Manus: pricing (JS-rendered)
- Manus: independence announcement
- Manus: Introducing Manus 2.0 (28 Sep 2026)
- Manus: Introducing Manus Flex (29 Sep 2026)
- Manus raises US$500M+ after the Meta unwind (Reuters via Yahoo Finance, 8 Oct 2026)
- testingcatalog: Manus 2.0 coverage
- Manus: Wikipedia (Meta saga timeline))
- HN: "ManusAI Joins Meta" thread
- r/ycombinator: What happened with Manus?
- UX Collective: Manus: Real or Hype?
- Firecrawl: best AI for research
- NewsCatcher: deep research tools
- Manus: architecture overview paper
- nocode.mba: Manus pricing (third-party)
- felloai: Manus pricing (third-party)
AI Scientist trail: primary sources → Nature paper → Nature news → v2 arXiv → first-publication blog → ICLR virtual talk → HN 41231490 → independent eval 2502.14297. Manus trail: manus.im → pricing/docs → X verification (tweet + Bitget/Odaily) → architecture chase (arXiv 2505.02024, gist, Medium "Inside Manus") → reception chase (HN, r/ycombinator, UX Collective, FAIR Institute, NewsCatcher, Firecrawl, r/AIAssisted) → status chase (independence blog, Wikipedia timeline); extended 12 Oct 2026 (US$500M+ raise via Reuters; Manus Flex blog).
CoreSR
- https://coresr.ai
- https://coresr.ai/pricing
- CoreSR: compare page (11 tools / 33 capabilities; TITAN-SR JCE note)
- TITAN-SR: Journal of Clinical Epidemiology (DOI; verified 5 Oct 2026)
- TITAN-SR preprint (SSRN 6732292)
- ResearchGate: TITAN-SR abstract (read 21 Sep 2026)
- Pitre Substack: AI for systematic review screening
- Pitre Substack: Welcome to CoreSR
- @CoreSRR
- @GuyattGH
- Annals of Intensive Care 2026: diuretic NMA citing CoreSR
- CoreSR YouTube
- Atlas: AI systematic-review tools roundup (CoreSR absent)
- Paperguide: AI tools for evidence synthesis (CoreSR absent)
CoreSR sources were appended outside the grid in the 3 Sep pass; moved into a proper group in the 14 Sep refresh (content unchanged).